In contrast to Burkitt lymphoma (BL), where MYC is almost exclusively fused to an immunoglobulin locus, up to 50% of MYC translocations in DLBCL involve non-immunoglobulin genes, including among others BCL6, PAX5, and IKZF1 [41, 42]. Here, MYC is linked to diffuse large B-cell lymphoma.