A recent study by Yamashita et al. [45•] also identified high PD-L1 expression in 72% of cases in a cohort of 25 g-NEC/MiNEN patients, while Yang et al. found high PD-L1 expression in 49% of 43 g-NECs, and this correlated with poorer prognosis [46]. The gene discussed is CD274; the disease is neuroendocrine carcinoma.