Finally, ALPS or ALPS-like features may also arise from the complementary effect of variants in CASP10 and in another non-FAS gene, such as CASP8 or TNFRSF13C (i.e., BAFF receptor, whose mutations are typically associated with common variable immunodeficiency, CVID) [73]. Here, CASP10 is linked to autoimmune lymphoproliferative syndrome.