CPT1A and hyperlipidemia: T-cell–derived miR-214 facilitates perivascular fibrosis in hypertension (122), nuclear miR-320 promotes lipid accumulation (hyperlipidemia) in the heart (123), and genome-wide DNA methylation profiling has discovered significant differences in promoter CpG islands in genes like HIF3A, CPT1A, CD38, PHGDH, ABCG1, SREBF1, CPT1A, PDX1 (124).