We also found that both AURKA and EZH2 were highly expressed in TP53-mutant HCC samples, suggesting the relationship of AURKA and EZH2 with TP53 mutation, corroborating a recent study in HCC cell lines and mice (Dauch et al., 2016; Caruso et al., 2019). Here, TP53 is linked to hepatocellular carcinoma.