CXCL10 and acute respiratory distress syndrome: Elevated IP-10/CXCL10 expression has been associated with severe outcomes in both SARS-CoV and MERS-CoV infection (47–50), and patients who develop ARDS following SARS-CoV or H5N1 avian influenza virus infection exhibit high levels of IP-10/CXCL10 in the lungs (47, 51).