The DFS of HCC patients with high AFP ratio was significantly longer than that of patients with low AFP ratio (AFP ratio high vs. AFP ratio low, 28.10 vs. 14.23 months, p < 0.0001; HR, 0.64, 95% CI, 0.52-0.78), and OS was also significantly prolonged (p = 0.0017; HR, 0.56, 95% CI, 0.37-0.84) (Figure 2). This evidence concerns the gene AFP and hepatocellular carcinoma.