AFP and hepatocellular carcinoma: Multivariate analysis indicated that AFP ratio > 17.8 was an independent predictor of DFS and OS of AFP-positive HCC patients (DFS, HR, 1.710, 95% CI, 1.422-2.056, p < 0.001; OS, HR, 2.004, 95% CI, 1.381-2.906, p < 0.001).