Taking into account the lack of normal samples in the TCGA database for some cancer types, we integrated the GTEx database for further analysis and the results showed that the expression level of SERPINH1 in the tumor tissues of ACC, BLCA, BRCA, CHOL, COAD, DLBC, ESCA, GBM, HNSC, KIRC, KIRP, LAML, LGG, LIHC, LUAD, LUSC, OV, PAAD, PRAD, READ, SKCM, STAD, TGCT, THYM, and UCS (all p < 0.001); UCEC (p < 0.01); and SARC, THCA (all p < 0.05) are much higher than the corresponding control tissues (Figure 1B). The gene discussed is SERPINH1; the disease is cancer.