KDR and infection: Weinkopff et al. (70) also found that infection with Leishmania major increases the expression of VEGFA and VEGF receptor-2 (VEGFR-2) at the site of infection, and it correlated with lesion size and parasite burden, suggesting that VEGFA-dependent lymphangiogenesis could be a mechanism that restricts tissue inflammation and contributes to the severity of leishmaniosis.