In parallel, the DEGs present in interleukin IL-7 and Ephrin A (erythropoietin-producing hepatocellular carcinoma) signaling and in the activation of inflammasome (interferon inducible protein activated by viral DNA) pathways (Supplementary Table 4S), have been previously implicated in various facets of cell development, lymphocyte activation, immune surveillance and autoimmunity (21–23). This evidence concerns the gene EPO and hepatocellular carcinoma.