We found that the baselines of BMI, WC, WHR, Fat%, VFA, SBP, FINS, 2h-insulin, HOMA-IR, TG, and UA were significantly higher in the subsequent new-onset MetS group than in the subsequent non-MetS group, while HDL-c was significantly lower (P < 0.05; Table 6). This evidence concerns the gene INS and metabolic syndrome.