Integrative analysis of our ATAC-Seq, H3K27ac and H2AZ ChIP-Seq data, together with a published E2F1 ChIP-Seq analysis of the U87 GBM cell line further supported the idea that E2F1 may bind to the enhancer element within H2AZ2 gene promoter in GSC (Supplementary Fig. S3E) [28]. Here, H2AZ2 is linked to glioblastoma.