To this end, we generated a query signature that comprised the low expression of H2AZ2-positively correlated genes and high expression of H2AZ2-negatively correlated genes in TCGA gliomas, and submitted this “anti-H2AZ2” gene signature to the Connectivity Map Analysis (CMA) (Fig. 5A and Supplementary Table S4). Here, H2AZ2 is linked to central nervous system cancer.