Five populations of platelets were visualized in this study, drawn from un-irradiated wild-type (WT) mice, irradiated mice transplanted with MLL-AF9-transformed HSPCs at two time points (1-week: pre-AML and 3-week: AML), and irradiated mice with normal bone BMT at the same two time points(1-week control and 3-week control) (Fig. 1). This evidence concerns the gene KMT2A and acute myeloid leukemia.