In contrast, increased SOX10 z-scores were associated with decreased OS of patients with late-stage (n = 192; hazard ratio [HR] = 1.186; 95% confidence interval [CI] = 1.006–1.397; p = 0.03), but not early-stage melanoma (n = 217; HR = 1.203; 95%CI = 1.008–1.436; p = 0.192) (Fig. 3b). This evidence concerns the gene SOX10 and melanoma.