DGAT1 and colonic neoplasm: DGATs are classified with DGAT1 and DGAT2 subfamilies in animals and additional DGAT3 subfamily in plants54–57 with DGAT2 mRNA being the major form of DGAT mRNAs in mouse adipocytes and macrophages25,58 but DGAT1 as the major one in the colon cancer cells53.