The log-ratio value of label 1 was significantly higher in IDH mutant than in wild-type gliomas (P < 0.05), and these labels were categorized as M. In contrast, the log-ratio values of labels 7–10 were significantly higher in IDH wild-type than in mutant gliomas (P < 0.05, P < 0.001, P < 0.001, and P < 0.01, respectively), and these labels were categorized as W. Other labels (2–6) were categorized as N. The radar charts of the individual normalized values of the four images for each label in the K = 10 class are shown in Fig. 2b. Here, IDH2 is linked to glioma.