In support of the role of proinflammatory IL-6 in COVID-19 patients, TCZ which is a recombinant humanized monoclonal anti-IL-6R antibody approved by FDA for the treatment of severe or life-threatening chimeric antigen-receptor-T-cell-induced cytokine release syndrome44, is being tested in COVID-19 patients21–24. This evidence concerns the gene IL6 and COVID-19.