Notably, recent work demonstrates that miR-125b promotes liver fibrosis and hepatic stellate cell activation by the activation of RhoA signaling [43], and our results also demonstrate that RhoA and Hippo signaling are involved in Tanshinone IIA-mediated effects on breast cancer cell stemness (data not shown, GSE156155). The gene discussed is RHOA; the disease is Hepatic fibrosis.