However, as shown in Fig. 4A, G, H a significant change in STARD13 expression is observed before a significant change in miR-125b (ie at 2.5 μM dose), we assumed that other miRNAs could be involved in Tanshinone IIA-mediated regulation on STARD13 expression as denoted in Fig. 3G, such as miR-9 and miR-10b that had been previously confirmed to target STARD13 as well by our group [21, 23], and miR-146a, miR-210, miR-25, miR-103 and miR-484 have been shown to promote tumor stemness [18, 46–50]. Here, STARD13 is linked to neoplasm.