In a patient with an unusually high WCC (247 cells/μl; lymphomonocytic with small amounts of neutrophils, plasma cells, and activated lymphocytes; CNS involvement) and a positive SARS-CoV-2-AI, IL-6 was determined in both the CSF (> 300 pg/ml) and serum (17.3 pg/ml), revealing a very high IL-6 CSF/serum ratio of > 17 (compared to a ratio of < 2.67 in 95% of German control subjects without neurological disease [46]). The gene discussed is IL6; the disease is nervous system disorder.