CLEC4E and acute kidney injury: A recent study reported that Mincle maintains the phenotype of M1 macrophage in acute kidney injuery (AKI) [19] and inhibition of Mincle as well as its signaling pathway in macrophage ameliorates the renal injury in AKI [21, 22], suggeting that Mincle is a potential target for the treatment of AKI.