UCHL1 and brain injury: They found that GFAP predicted CT abnormalities with highest discrimination ability (AUC 0.89), better than any other single candidate protein or combination of biomarkers in their panel.110 Likewise, the NCAA-CARE Consortium tested a panel of four candidate biomarkers (GFAP, UCH-L1, NfL, and t-tau) in 366 athletes and found that a combination of GFAP and UCH-L1 yielded the highest diagnostic discrimination (AUC = 0.71) between acute sports concussion and contact sports controls.111