At the same time, in rats in the IGT group, the activity of this enzyme in the mucosa was increased in the duodenum (by 2.0 times, compared with the HFD group), in the jejunum (in its distal part) (by 66.0, 74.3 and 53.0% compared with the SCD, HFD and T2D groups, respectively, p < 0.05), in the ileum (by 59% compared to the SCD group, p < 0.05,) and in the colon (2.0 times compared to the HFD group, p < 0.05). The gene discussed is SCD; the disease is Schnyder corneal dystrophy.