Meta-analysis from Mohammed et al. and Rudbane et al. did not show significant decrease of CRP (respectively, SMD (95% CI) −2.660 mg/L (−6.144 to 0.823), p = 0.134, I2 = 82%; SMD (95% CI) −0.27 mg/L (−0.77 to 0.23), p = NS, I2 = 55%), pooling 191 and 132 RA patients. This evidence concerns the gene CRP and rheumatoid arthritis.