Besides RYR, other natural compounds could be effective strategies in the treatment of MS and prevention of MS progression towards serious complications through the inhibitory activity of the enzymes associated with carbohydrate/lipid digestion and cardiometabolic diseases (i.e., α-amylase, α-glucosidase, HMG-CoA reductase, and pancreatic lipase) [18,19,20]. This evidence concerns the gene HMGCR and myeloid sarcoma.