One of the studies showed various potential hits for five different protein targets of COVID-19, including the coronavirus 3C-like protease (3CLpro), RNA dependent RNA polymerase (RdRp), angiotensin-converting enzyme 2 (ACE2), papain-like protease (PLpro), and spike glycoprotein-receptor binding domain (SGp-RBD), based on the results of docking scores, in silico ADMET properties, drug-likeness properties, and protein–ligand interaction study [142]. Here, ACE2 is linked to COVID-19.