TNFSF10 and chronic myelogenous leukemia, BCR-ABL1 positive: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/TNFSF10), which was shown to induce apoptosis in many tumor cells but not in normal cells [91,92,93], is downregulated in CML patients, particularly in more advanced phases of the disease [90,94].