It has been reported to be deregulated in breast cancer [38] and ovarian cancer [39], while a recent report showed its role in HCC, where a significant correlation was found between the levels of miR-661 and the expression of NF-κB-p65 and hepatitis B virus transactivator protein (HBx) in a human HCC cell line through HBx-mediated stimulation of metastasis-associated protein 1 (MTA1) [40]. This evidence concerns the gene NFKB1 and breast cancer.