CD8A and neoplasm: Furthermore, combination treatment of PDT with a synthetic long peptide (SLP) vaccine, covering T-cell (CD4 and CD8) epitopes of tumor antigens (i.e., from the human papillomavirus (HPV)16 E7 oncoprotein), has been regarded as a prospective treatment method for oncogenic virus-induced cancers (e.g., HPV or leukemia virus).