INS and type 2 diabetes mellitus: In another study, the insulin-sensitizing effect of Scutellaria baicalensis (SB) was proposed as an adjunct to metformin in the treatment of type 2 diabetic patients and also indicates that SB improves metabolism and the number of microbial taxa, which suggests that this treatment can improve glucose metabolism through modulation of the gut microbiota in patients with T2D [20].