ICAM1 and breast cancer: With the use of LFA1-P peptide to mimic the ICAM-1-targeted endogenous ligand LFA-1 and the demonstrated expression of breast cancer cell 4T1, we have successfully developed and characterized ICAM-1-targeted DcNPs containing G and T. We found that by coating DcNPs containing GT with 1% LFA1-P, the GT DcNP LFA1-P can be made reproducibly in nano-drug particles with an approximately 60 nm diameter.