TNF and atherosclerosis: Twenty-two druggable genes were enriched in the lipid and atherosclerosis pathway (8.4 × 10−13), 19 in the JAK-STAT signaling pathway (6.2 × 10−12), 17 in the Th17 cell differentiation pathway (5.2 × 10−13), 17 in the IL-17 signaling pathway (6.0 × 10−14), 16 in the inflammatory bowel disease pathway (1.5 × 10−16), 14 in the TLR signaling pathway (6.0 × 10−14), 14 in the C-type leptin receptor signaling pathway (2.4 × 10−9) and 13 in the TNF signaling pathway (8.4 × 10−8).