FixVac is an intravenously administered liposomal RNA (RNA-LPX) vaccine, which consists of four naked RNA molecules encoding New York Esophageal squamous cell carcinoma 1 (NY-ESO-1), melanoma-associated antigen A3 (MAGE-A3), tyrosinase, and transmembrane phosphatase with tensin homology (TPTE), aiming at TAAs of melanoma. This evidence concerns the gene TPTE and melanoma.