It is worth mentioning that patients with CKD have high levels of FGF-23 in the blood [64] and lower expression of Klotho and fibroblast growth factor receptor (FGFR) one in the parathyroid glands [65], although Hofman-Bang, J., et al., have described the higher expression of Klotho in the latter organ [66]. Here, FGF23 is linked to chronic kidney disease.