Although only the inhibition of LTA4H epoxide hydrolase activity has been related to anti-cancer effects, there is no evidence that the inhibition of aminopeptidase would bring any beneficial effects; therefore, three strategies can be used to inhibit this enzyme: (1) selective inhibition of epoxide hydrolase; (2) selective inhibition of aminopeptidase; and (3) aminopeptidase-sparing LTA4H inhibitors that bind to the hydrophobic tunnel where the long hydrophobic tail of LTA4 is buried. The gene discussed is CPQ; the disease is cancer.