JMJD6 and colon carcinoma: Recently, Yang and colleagues compilated a series of studies relating the abnormal overexpression of JMJD6 in several different cancers (e.g., Breast cancer, Melanoma, Oral cancer, Glioblastoma, Hepatocellular carcinoma, Colon carcinoma, Ovarian cancer, Neuroglioma, etc.)to increased cancer cell proliferation and invasion leading to aggressive tumors and poor prognosis [138].