Tumor cells undergo apoptosis due to the disruption of the integrity of their membranes by peptides, likely inducing the activation of apoptotic factors through the G-protein-coupled receptor (GPCR): AIF, Bax, Bak, Puma, and p53, as shown in HCT116 colorectal cancer cells [37]. Here, AIFM1 is linked to colorectal cancer.