Systemic inflammation is another validated bedside predictor of adverse outcomes in cancer patients with COVID-19; accordingly, hypoalbuminemia (escape of albumin to the interstitial space due to inflammation-increased capillary permeability) and lymphocytopenia (reduction of lymphocytes due to systemic inflammation and direct neutralization) are independently predictive of severe COVID-19 in cancer patients, as computed by the OnCovid Inflammatory Score [46,47]. This evidence concerns the gene ALB and cancer.