social behavior, anxiety, COVID-19, pandemic, psychological impact, depression, mental health, comfort food, neurophysiological mechanism, intrinsic reward mechanism, hyperpalatable food, obesity, inflammation, visceral weight gain, cardiovascular, adipose tissue, complications, calories, nutrient density, hunger, insulin resistance, cancer, body mass index (BMI), intensive care unit, SARS-Cov-2. Here, INS is linked to Obesity.