Meanwhile, a recent meta-analysis investigating the ADRB3 gene Trp64Arg polymorphism showed that carriers of the mutated 64Arg allele consistently and significantly had higher CHD risk compared to subjects harboring the wild-type 64Trp allele, with the allelic (OR: 1.48), additive (OR: 2.66), and recessive models (OR: 2.46) [87]. The gene discussed is ADRB3; the disease is coronary artery disorder.