NOS3 and type 2 diabetes mellitus: When assessing the variant association with other parameters, the study reported that subjects with eNOS –786C were more likely to have BMI more than 25 kg/m2 (OR: 2.00), positive family history of T2D (OR: 1.99), hypertension (OR: 1.90), and being an active smoker (OR: 2.81) [59].