The mutated genes associated with lymph node metastasis were SECISBP2L (p = 2.20e-16, r = 1.000) and KDM5C (p = 0.00038, r = 0.690); both of these showed a very strong association (Tables S7 and S13). Here, KDM5C is linked to metastatic malignant neoplasm in the lymph nodes.