The most requested by our panel were cardiovascular markers (troponin, BNP or NT-proBNP, and D-dimers), in connection with major cardiac emergencies (infarction, cardiac respiratory distress, and pulmonary embolism) and the fact that a biological result can influence the management and orientation of a patient by excluding a diagnosis due to its negative predictive value. This evidence concerns the gene NPPB and Respiratory distress.