In detail, data from genome-wide studies highlight that the common rs4846914 SNP at the GALNT2 locus, which is associated with lower GALNT2 expression in human liver [9], is also associated with increased TG and lower HDL-C levels [14], a combination known as atherogenic dyslipidemia, which is a marker of insulin resistance and an established risk factor for coronary artery disease (CAD) [81,87]. The gene discussed is GALNT2; the disease is Insulin resistance.