The mutation present in EGFRvIII cells is characteristic of GBM since 40% of glioblastoma cells have a mutation that overexpresses EGFR, of which about 50% is the EGFRvIII variant, which results in uninterrupted activity of the receptor without the need for external stimulation [215,216,217,218,219,220]. This evidence concerns the gene EGFR and glioblastoma.