The data respecting the correlation between CA9 and different types of cathepsins (CTSB, CTSD, CTSK, CTSL1, CTSL2, CTSS) were inconsistent, so we focused on the expression of CTSD in AAA tissues and revealed that 82% of CA9-positive tissues were positive for CTSD mRNA. The gene discussed is CTSS; the disease is triple-A syndrome.