In addition, THZ1, a covalent inhibitor of CDK7, reduces viability of a broad range of cancer cell lines from different entities, including thyroid carcinoma, lung squamous cell carcinoma, cervical cancer, colorectal cancer and pancreatic cancer, with T-cell acute lymphoblastic leukemia cells being especially sensitive [23,24,25,26,27]. The gene discussed is CDK7; the disease is familial pancreatic carcinoma.