PFKP and breast cancer: The suppression of PFKP is responsible for the deviation of G6P into the PPP and, thus, for the production of NADPH, an antioxidant co-factor, the availability of which is linked to the survival of BC cells exposed to oxidative stress (Figure 2) [49].SNAIL ⇒ PFKP ↓ ⇒ PPP ↑ ⇒ NADPH ↑ ⇒ survival to oxidative stress