INS and metabolic syndrome: In addition to regulating insulin secretion and pancreatic β-cell proliferation and adaptation to metabolic stress [134], miR-17-5p was reported by Ramzan et al. to have a negative association with BMI and waist circumference, which was in concordance to previous studies [125], thus confirming the potential correlation between miR-17-5p and central adiposity, an important feature of MetS.