As an example, the interaction between XIST and miR-34a has been validated in different cell contexts, and implicated in nasopharyngeal carcinoma and colon and thyroid cancer, by networking with different mRNA targets, i.e., E2F3, WNT1 and MET, respectively [65,81,82], as shown in Table 1. The gene discussed is MET; the disease is thyroid cancer.