The oncogenic role of XIST has also been coherently reported by different papers studying another tumors of the nervous system: in glioma tissues and cell lines, XIST is significantly upregulated and related to poorer clinical and pathologic features and shorter survival time; its knockdown inhibits cell proliferation, migration and invasion in vitro and reduces tumor growth in vivo [75,76,77,78]. The gene discussed is XIST; the disease is glioma.