Among these, the Amuc_1434* degrades mucin 2 in colon cancer cells and promotes apoptosis of human colon cancer LS174T cells [58,59], and its specific outer membrane protein Amuc_1100 can inhibit colitis-associated colorectal cancer by regulating CD8+ cytotoxic T lymphocytes [60]. This evidence concerns the gene CD8A and colonic neoplasm.