In addition, in vivo experiments have shown that knockdown of carnitine palmitoyltransferase 1A (CPT1A), which is the rate-limiting enzyme for FAO, or diacylglycerol-acyltransferase 1 (DGAT1), responsible for storing excess FAs in lipid droplets [32], reduce the rate of tumor growth and increased survival in xerograph mouse GBM model [32,42]. The gene discussed is CPT1A; the disease is neoplasm.