Many of the affected genes (e.g., Add3, Cacna1d, Camk2b, Fermt2, Gabrg2, Grip1, Kcnd3, Sorbs1, and Stx2) are regulated by MBNL proteins, and they are also misregulated in other DM1 mouse models and human tissues [47,63,64,65,66,67]. The gene discussed is ADD3; the disease is myotonic dystrophy type 1.