Many of the affected genes (e.g., Add3, Cacna1d, Camk2b, Fermt2, Gabrg2, Grip1, Kcnd3, Sorbs1, and Stx2) are regulated by MBNL proteins, and they are also misregulated in other DM1 mouse models and human tissues [47,63,64,65,66,67]. This evidence concerns the gene GRIP1 and myotonic dystrophy type 1.